The nation witnessed 497,151 new confirmed cases on Saturday, bringing the national count to 54,743,993 as numbers have persisted in reaching new records in the past month.
In terms of the death toll, 1,235 have been registered, bringing the count to 825,536 - beating last month's previous record.
This comes after a study by Columbia University showed that Omicron-fueled cases could peak to roughly 2.5 million by January 9, with others estimating the surge to go to 5.4 million.
According to Governor Kathy Hochul, NYC has continued to shatter records with 85,476 new cases reported in the state.
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These numbers quadrupled in size, which previously registered a total of 21,027 positive cases just a couple of weeks earlier.
Hospitalizations in the state have further leaped to 8,451, with medical center beds persisting in becoming scarce as the virus swarms around the city.
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The growth in the city's cases have further increased the death rate with 81 registered as of Saturday.
NYC Mayor Eric Adams, who was sworn in early Saturday morning, is working on guaranteeing the health and safety of the city's residents in the ongoing battle against the virus.
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After being sworn in as New York City mayor, Eric Adams assured New Yorkers that the city would not be controlled by crises as it grapples with a continuing surge in COVID-19 infections.
"Getting vaccinated is not letting the crisis control you," Adams announced at City Hall.
"Enjoying a Broadway show. Sending your kids to school. Going back to the office. These are declarations of confidence that our city is our own."
While the new mayor has vowed to keep the city open and stave off any retraction to shutdowns, he is taking the helm of a city that has seen subway lines, restaurants and even urgent care centers temporarily close because of staffing shortages caused by the virus.
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Adams announced this week that he plans to keep in place many of the policies of outgoing Mayor Bill de Blasio, including vaccine mandates that are among the strictest in the country.
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The wave of the new variant has caused the international public to panic over fears of how it might cripple the economy in the new year, as evident throughout the beginning stages of the pandemic.
Adams announced he and advisers are studying whether to expand vaccine mandates and plan to distribute face masks and rapid tests and introduce a color-coded system alerting New Yorkers to the present threat level.