She was heard shouting messages in favor of abortion rights through a megaphone.
However, before the activist could end a sentence a Secret Service agent in a police jacket seized her and pinned her onto the street.
America's abortion divide was sparked by the leak last month of a draft Supreme Court opinion indicating it will overturn the landmark abortions ruling Roe v Wade.
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The 5-4 vote saw five of the six Republican-appointed justices side with the state of Mississippi in the case Dobbs v. Jackson Women's Health.
Mississippi asked the court to lower the abortion limit to 15 weeks before requesting the scuttling of those protections, granted by Roe v Wade, altogether.
The young protestor seemed to have been radicalized by that news, grappling with the agent and pulling off his hat and glasses. Another officer came along and pinned her down.
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The woman was then cuffed and arrested.
She was heard saying: "An abortion ban will not stop abortions - only safe ones."
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"Get the f*** off of me!"
Secret Service chief of communications Anthony Guglielmi said: Shortly after 5pm, an adult female entered a restricted roadway along a motorcade route on Chick Hearn Ct in Los Angeles.
"As the woman approached passing vehicles, a United States Secret Service agent swiftly removed her from the roadway and placed her into custody."
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"There was no impact to the motorcade movement or our protectees. Our investigation into this incident is ongoing."
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The pro-choice Biden administration is in favor of abortion rights as the Supreme Court reportedly mulls overturning Roe v Wade.
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The landmark 1973 court decision legalized abortions across America - but is now reportedly in danger.
Biden told Jimmy Kimmel late Wednesday that Democrats must "legislate"' to preserve women's rights in the event the Supreme Court overturns the ruling.
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He explained: "If [the court's rumored to overturn] occurs, I think we will have to legislate it. We're looking into it right now."
"It's just ridiculous, in my view. I don't think the country will stand for it."
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"It's going to cause a mini-revolution and they're going to vote a lot of these folks out of office."
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It came as a heavily armed 26-year-old man was detained Wednesday near Supreme Court Justice Brett Kavanaugh's house.
He supposedly told authorities he wanted to kill the conservative jurist and then himself.
The attempted murderer was identified as Nicholas John Roske of Simi Valley, California.