A total of 270 experts and medical professionals called on the streaming giant to adopt a misinformation policy after the comedian hosted the controversial Dr. Robert Malone last month.
During a three-hour, six-minute interview on the now-viral episode #1757 of The Joe Rogan Experience, Malone compared the U.S. to Nazi Germany and suggested today's society was suffering from a "mass formation psychosis" over the use of vaccines.
He also claimed to be part of the team that invented the mRNA technology used in the COVID-19 jab and asserted pharmaceutical companies administering vaccines - such as Pfizer and Moderna - have "financial conflicts of interest."
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Hundreds of medical professionals went on to fact-check Malone and have demanded accountability from Spotify - which spent a reported $100million on exclusive streaming rights to the Joe Rogan Experience last year.
In an open letter, they wrote: "With an estimated 11 million listeners per episode, JRE, which is hosted exclusively on Spotify, is the world's largest podcast and has tremendous influence.
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"Spotify has a responsibility to mitigate the spread of misinformation on its platform, though the company presently has no misinformation policy."
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The letter alleges Rogan has a penchant for "broadcasting misinformation, particularly regarding the COVID-19 pandemic" and that the episode with Malone promoted "baseless conspiracy theories," including "an unfounded theory that societal leaders have 'hypnotized the public'."
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The letter goes on: "Dr. Malone is one of two recent JRE guests who has compared pandemic policies to the Holocaust.
"These actions are not only objectionable and offensive, but also medically and culturally dangerous."
In the episode posted on New Year's Eve, Malone, 61, said: "It was from, basically, European intellectual inquiry into what the heck happened in Germany in the 20s and 30s. Very intelligent, highly educated population and they went barking mad.
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"And how did that happen? The answer is mass formation psychosis. When you have a society that has become decoupled from each other, and has free floating anxiety, in a sense that things don't make sense. We can't understand it."
"And then their attention gets focused by a leader or series of events on one small point, just like hypnosis. They literally become hypnotized and can be led anywhere."
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Streaming giant YouTube removed the episode from its platform, while Malone's Twitter account - followed by 500,000 twitter users - was suspended hours before appearing on the show for "violating" its rules.
The episode was still available on Spotify on Thursday. Dailymail.com has contacted Spotify and the Joe Rogan Experience for comment.
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