"Now I can't promise that every person will get every gift they want on time - only Santa Claus can keep that promise," Biden announced, continuing that "there are items every year that sell out that are hard to find."
He stressed that "some of you moms and dads may remember Cabbage Patch Kids in the 80s or Beanie Babies in the 90s," when short supplies meant they were hard to come by.
"But we're heading into a holiday season in very strong shape," he stated, adding he thought store shelves would be stocked.
The President spoke to encourage Americans that shelves will be stocked over the holidays and maintained the supply chain disaster was coming to an end.
Yet, there are concerns that the emergence of the Omicron variant could keep people working from home and hit demand. The first case of the mutant strain in America was confirmed in California on Wednesday.
Biden is supposed to reveal a new plan to battle COVID this winter on Thursday that he claims will not include any more lockdowns and shutdowns and will be focused on getting more booster shots to Americans and mask-wearing indoors.
The White House has faced spiraling inflation and backlogs at ports that have been compounded by the pandemic.
Gas prices have been rising, urging Biden to tap into the strategic oil reserves to release 50 million barrels of oil.
He reflected on his meeting early this week with CEOs of major retail companies including Walmart, Best Buy, CVS, and Mattel, who announced they are "ready to meet demand for the holidays."
UPS and FedEx have stated that they are on track to deliver their most packages in history, Biden explained.
"I don't want to speculate on anybody's motives, but it's always easier to complain about the problem than try to fix it," Biden announced.
"Imagine rooting for a higher cost for American families just to score a few political points?" Biden asked.
Biden pointed to the highlights of the Build Back Better bill, which includes universal pre-K, capping childcare costs, an extension of the child tax credit, and other social infrastructure goodies.