The Real Time host also denounced the far-left ‘Squad’ member on Friday for dismissing critics of ‘wokeness’ - which he claims is the reason Democrats suffered electoral defeats this year in Virginia and elsewhere.
Maher declared he would 'love' for Ocasio-Cortez to appear on his show since there's 'so much to admire' about her, particularly her efforts to combat climate change.
'But that will probably never happen because Democrats don't go anywhere these days where they're not being adored,' Maher went on to note.
'And that's my last bit of advice to them. Go where the "amen corner" isn't.
'Do Fox News. Be brave. Come here. Go everywhere.'
Maher continued: 'Winning is about expanding the electorate.'
The HBO talker also hit out at Ocasio-Cortez and the Democratic Party for turning ‘woke’ into a ‘pejorative’ that has turned off voters.
'If the word only made you think of rational, deserved causes like teaching a less whitewashed version of American history, AOC would still want to own it,' Maher insisted.
'But it's a joke because it makes you think of people who wake up offended and take orders from Twitter.
'And their oversensitivity has grown tiresome.'
In his monologue on Friday’s show, Maher acknowledged that Ocasio-Cortez rejected criticism from political strategist James Carville that Democrats’ touting of ‘stupid wokeness’ hurt them at the polling stations.
The congresswoman from Queens and the Bronx tweeted earlier this month that the term ‘woke’ was primarily used by ‘older people.’
``Like the average audience for people seriously using the word "woke" in a 2021 political discussion are James Carville and Fox News pundits so that should tell you all you need to know,' Ocasio-Cortez wrote in a tweet from earlier this month.
She lashed out at Carville, a former top adviser to Bill Clinton, tweeting: ‘And before people disingenuously complain “woke” is denigrating to older people, it’s actually pundits like Carville using terms like “woke” to insult voters under 45 that’s denigrating.’
She added: 'Don’t wonder why youth turnout falls when Dems talk about them like this. We need everyone.'
Ocasio-Cortez was reacting to an interview that Carville gave to PBS News House to discuss Republican Glen Youngkin's victory over Democrat Terry McAuliffe in the Virginia gubernatorial race.
Republicans also captured the state legislature in Virginia, which a Democrat majority had previously led.
The election in Virginia and other races nationwide this year has political observers predicting that the GOP will take back the House and the Senate next year.