The comments came during a panel talk on this year's final episode of HBO's Real Time with Bill Maher.
During the talk, Maher clashed with Jon Meacham, a speechwriter for President-elect Joe Biden, former MSNBC contributor, and presidential historian.
"It's easy, because it seems so incompetent, to make fun of it, but this is an administration whose fundamental incompetence has led to the deaths of hundreds of thousands of people and the most significant weakening of institutions that, however flawed, have produced, by and large, a more perfect union.
"So it's easy to be amused by Rudy, but we're just lucky that our authoritarians are so incompetent."
Maher then rushed to claim that the United States' coronavirus-related deaths were a result of public failure - not just President Trump.
"Everybody's incompetent. It wasn't just Trump that led to those deaths," said Maher. "He certainly did his part, but we're an incompetent country."
"That's true," Meacham, 51, agreed.
"And an unhealthy one," Maher said.
The United States has recorded more than 11.9 million cases and an increasing death toll of 254,451.
Most recently, the president's oldest son, Don Jr., announced he tested positive for coronavirus before going on a trip with his son.
The United States' battle with the virus will probably decrease as soon as December.
On Friday, Pfizer Inc. declared it will ask for emergency use authorization of its COVID-19 vaccine with the Food and Drug Administration.
The application to the FDA comes just days after Pfizer and German partner BioNTech SE reported final trial results that showed the vaccine was 95 percent effective in blocking COVID-19 with no major safety concerns.
The companies expect the FDA to grant emergency use by mid-December and said they will begin shipping doses almost immediately.
MSNBC contributor Jon Meacham has been dismissed by the network after he failed to admit that he had been helping write President-elect Joe Biden's speeches.
Meacham, a historian, and Pulitzer Prize-winning biographer has been a regular writer for the network, where he has made debuts on Morning Joe, Deadline, and The 11th Hour with Brian Williams.
The political commentator had most recently appeared on air to comment on the presidential election as well as Biden's victory speech on Saturday night.
Meacham, however, did not tell his employers that he himself had been included in writing Biden's speeches, including his acceptance address in Wilmington.
The report showed Meacham had been "playing a larger role" in Biden's campaign "than was previously known", including writing the president-elect's approval speech at the Democratic National Convention this summer as well as his speech in Gettysburg last month.